Manuscripts

Broglio F, E Arvat, A Benso et al. Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans. J Clin Endocrinol Metab 86: 5083-5086, 2001

Broglio F, C Gottero, F Prodam et al. Non-acylated ghrelin counteracts the metabolic but not the neuroendocrine response to acylated ghrelin in humans. J Clin Endocrinol Metab. 89(6):3062-5, 2004.

Gauna C, M Meyler, J Janssen et al. Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity. J Clin Endocrinol Metab 89:5035-5042, 2004.

Gauna C, P Delhanty, L Hofland et al. Ghrelin stimulates, whereas des-octanoyl ghrelin inhibits, glucose output by primary hepatocytes. J Clin Endocrinol Metab 90: 1055-1060, 2005.

Gauna C, P Delhanty, MO Van Aken et al. Unacylated ghrelin is active on the INS-1E rat insulinoma cell line independently of the growth hormone secretagogue receptor type 1a and the corticotropin releasing factor 2 receptor. Mol Cell Endocrinol. 7;251:103-11, 2006.

Gauna C, Kiewiet RM, Janssen JA et al. Unacylated ghrelin acts as a potent insulin secretagogue in glucose-stimulated conditions. Am J Physiol Endocrinol Metab 293(3):E697-704, 2007

Granata R, F Settani, F Catapano et al. Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3',5'-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-Kinase/Akt signaling. Endocrinology  148(2):512-29, 2007

Posters

Broglio F, F Prodam, F Riganti et al. Unacylated ghrelin enhances the early insulin response to meal, improves glucose metabolism and decreases free fatty acids levels. Endo2007, Toronto, June 2007.